Polyunsaturated lipid senolytics exploit a ferroptotic vulnerability in senescent cells

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slice backing store of the correct size, and append never has to do

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32 entries may sound small by modern standards (current x86 processors have thousands of TLB entries), but it covers 128 KB of memory -- enough for the working set of most 1980s programs. A TLB miss is not catastrophic either; the hardware page walker handles it transparently in about 20 cycles.